Phasor imaging with a widefield photon-counting detector

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Phasor-based single-molecule fluorescence lifetime imaging using a wide-field photon-counting detector.

Fluorescence lifetime imaging (FLIM) is a powerful approach to studying the immediate environment of molecules. For example, it is used in biology to study changes in the chemical environment, or to study binding processes, aggregation, and conformational changes by measuring Förster resonance energy transfer (FRET) between donor and acceptor fluorophores. FLIM can be acquired by time-domain me...

متن کامل

Photon counting with a loop detector.

We propose a design for a photon-counting detector that is capable of resolving multiphoton events. The basic element of the setup is a fiber loop, which traps the input field with the help of a fast electro-optic switch. A single weakly coupled avalanche photodiode is used to detect small portions of the signal field extracted from the loop. We analyze the response of the loop detector to an a...

متن کامل

Photon -counting Reticontm Detector

For applications in faint -object spectroscopy at the Mt. Hopkins Observatory, a photon counting detector has been built using a dual 936 Reticon diode array fibre -optically coupled to a high -gain image intensifier package. The electronic signal processing follows closely the design of Shectman; the diode array is scanned every millisecond, each frame is subtracted from the previous to minimi...

متن کامل

Photon-Counting H33D Detector for Biological Fluorescence Imaging.

We have developed a photon-counting High-temporal and High-spatial resolution, High-throughput 3-Dimensional detector (H33D) for biological imaging of fluorescent samples. The design is based on a 25 mm diameter S20 photocathode followed by a 3-microchannel plate stack, and a cross delay line anode. We describe the bench performance of the H33D detector, as well as preliminary imaging results o...

متن کامل

Small-angle scatter tomography with a photon-counting detector array.

Small-angle x-ray scatter imaging has a high intrinsic contrast in cancer research and other applications, and provides information on molecular composition and micro-structure of the tissue. In general, the implementations of small-angle coherent scatter imaging can be divided into two main categories: direct tomography and angular dispersive computerized tomography. Based on the recent develo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biomedical Optics

سال: 2012

ISSN: 1083-3668

DOI: 10.1117/1.jbo.17.1.016008